ceesdekker.net for Dummies
ceesdekker.net for Dummies
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Halfway by his profession, Cees Dekker reinvented himself. Just after a long time of hardcore physics, he shifted his aim to ‘nanobiology’ with the transform in the millennium. A time period he coined himself, like a make any difference of reality.
Our team experiments bacterial mobile division and is particularly aiming to represent a ‘base up biology’ in synthetic cells that will autonomously divide. Our primary desire lies in mobile division, chromatin construction, and spatial Manage.
, Groningen scientists current the outcome in their initiatives for making labs extra sustainable and supply methods for other labs.
2007, very first serious-time detection of strand exchange in homologous recombination by RecA; discovery of a very low persistence length of ends of microtubules; and solved the system of biosensing with carbon nanotubes
2015, discovery that condensin is actually a hugely flexible protein composition; and initially detection of DNA knots working with nanopores
Immediate immobilization of native yeast iso-1 cytochrome c on bare gold: fast electron relay to redox enzymes and zeptomole protein-movie voltammetry
Considering the fact that 2000 he moved to one-molecule biophysics and nanobiology, with investigation from DNA supercoiling scientific studies of nucleosomes and DNA restore proteins to DNA translocation through nanopores. A short while ago his exploration has focused on studying cell division with microbes on chip, though his best curiosity is in the course of acknowledging synthetic cells.
Atomic force microscopy exhibits that vaccinia topoisomerase IB generates filaments on DNA in a very cooperative manner
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At the moment, we also realized that it should be feasible to make use of a single semiconducting carbon nanotube to make a transistor — and we established out to really make it. We stretched specific semiconducting nanotubes across metallic electrodes and utilized the underlying silicon substrate to be a gate electrode, creating The fundamental 3-terminal layout of the discipline-result transistor (Fig.
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Cees Dekker is Distinguished College Professor at TU ceesdekker Delft. Experienced being a physicist, he pioneered nanotechnology with several discoveries on carbon nanotubes within the nineteen nineties. Considering the fact that 2000, he moved to solitary-molecule biophysics and nanobiology. His existing research concentrates on (i) nanopores for protein sequencing; (ii) chromosome construction, in particular SMC motor protein; and (iii) developing a residing synthetic mobile from lifeless molecules. Dekker is surely an elected member of the KNAW and fellow to your APS along with the IOP.
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Illustration (2) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in grey, the rim of the pore is highlighted in purple, along with a 3D rendering with the motion on the DNA rod is displayed.